OstaPro by Genetixx Labs

(Ostarine)

Formerly Matrix Labs

 60 capsules per bottle

PER CAPSULE

Osta - 15mgs

Ostarine Benefits

Muscle Size & Strength

Ostarine mimics anabolic steroids’ anabolism, by stimulating the AR (androgen receptor), increasing skeletal muscle and bone strength.

Ostarine also enhances satellite cell cycle activation, resulting in fusing with myofibres and increasing myonuclei in the muscles.

Due to ostarine’s tissue selective properties, it can increase lean muscle, without inducing the androgenic side effects of steroids — preventing benign prostatic hyperplasia (BPH).

In one study on elderly men and women, participants increased their lean body mass by 3%, after taking 3mg/day of ostarine for 12 weeks (1). This is the equivalent of an 80kg (176lb) man gaining 2.4kg (5.3lbs) of muscle.

These results are encouraging considering the dosage used (3mg/day) is only a fraction of what weightlifters administer to improve their body composition.

These elderly men and women also experienced significant increases in muscular strength, adding 22lbs to their bench press by the end of the 12 weeks.

No Virilization in Women

Women are particularly vulnerable to virilization effects when taking steroidal compounds; however, ostarine appears to be safe in this regard; with elderly women in the above-cited study experiencing no masculinization effects.

Fat Loss

Ostarine is an effective SARM for cutting, due to it improving insulin sensitivity and thus inducing subcutaneous and visceral fat loss.

Reductions in visceral fat are a unique attribute on ostarine, in contrast to many anabolic steroids, which can increase VF.

This is why some steroid-users have a protruding appearance to their waistline, indicative of high visceral fat levels.

However, on ostarine you will notice fat loss all over the body, particularly prominent in the midsection; reducing overall waist size.

Ostarine also has positive metabolic effects, increasing calorie expenditure throughout the day and improving the chances of users eating in a calorie deficit. Thus, it has direct and indirect lipolytic effects.

In the elderly study, users experienced a 0.6kg (1.3lbs) reduction in fat mass. It is fair to assume this quantity of fat loss will be more pronounced in non-elderly persons, who combine ostarine with regular weightlifting and cardiovascular exercise.

Ostarine Side Effects

Ostarine does not appear to cause hypertrophy of the prostate, however it does reproduce several steroid side effects (detailed below).

Testosterone Suppression

In the elderly study cited, the men taking 3g/day of ostarine for 12 weeks experienced minimal fluctuations in serum testosterone levels.

Weightlifters utilizing higher dosages of ostarine have reported normal libido, nocturnal erections and testicular size — when taking 25mg/day for 6 weeks (2).

However, other ostarine users have reported low testosterone levels post-cycle, with one user scoring 148 ng/dL, compared to an average score of 264-916 ng/dL (for his age range). This was following 20mg/day of ostarine for 8 weeks (3).

Thus, based on existing research and anecdotal evidence it is reasonable to conclude that ostarine has no significant effect on endogenous testosterone levels, when taken in very small dosages. However, in higher dosages it may have a significant suppressing effect; which may not always be obvious to users (unless being tested), and may depend on how the compound affects the individual (potentially differing on a case-to-case basis).

Liver Toxicity

In the elderly study, AST/ALT liver markers increased above normal levels in 20% of participants, indicating ostarine’s hepatotoxic potential. Although levels did not rise to exceedingly dangerous levels, it is worth noting that such participants only took a fraction of the dose compared to gym-goers taking ostarine for physique-enhancing purposes.

Ostarine’s liver toxicity may be due to it being administered orally (swallowed via the mouth) and thus having to bypass the liver, before becoming fully active; increasing stress and inflammation to this organ.

We also understand from research that other SARMs such as: LGD-4033 (ligandrol) and RAD-140 (testolone) have the potential to cause hepatocellular–cholestatic liver injury (4).

Cholesterol Issues

HDL cholesterol (the good type), was reduced by 27% when taking 3mg/day of ostarine for 12 weeks. This is alarming, considering the tiny dosage used in this study; thus ostarine has the potential to increase myocardial infarction (heart attack) risk in the short or long-term — even in modest doses.

Ostarine and other SARMs’ ability to skew HDL/LDL cholesterol levels may be attributed to their oral nature; thus stimulating hepatic lipase in the liver upon entry — an enzyme known for decreasing HDL and increasing arterial plaque.

Gynecomastia and Water Retention

Some SARMs can elevate estrogen indirectly, with them binding strongly to the androgen receptor; leaving more natural testosterone available to convert to estrogen.

Consequently, some people have complained of bloating or gynecomastia when using SARMs, despite a lack of the aromatase enzyme present.

However, ostarine-users often report minimal water retention, but instead a dry-looking physique. Improved insulin sensitivity also indicates ostarine’s minimal effect on this female sex hormone; thus the risks of developing gynecomastia are thought to be low.

One user confirmed this by testing his estradiol levels post-ostarine cycle (5); they measured at a normal level, being 17.4 pg/mL (average range: 7.6-42.6 pg/mL). 

Hair Loss

Some ostarine-users do report hair loss or recession during their cycle (6), despite the 5-alpha reductase enzyme not being present with ostarine or other SARMs.

The reason hair loss occurs is due to elevated DHT (dihydrotestosterone) levels, which are raised indirectly. When ostarine competes with your natural testosterone levels for binding to the androgen receptor, ostarine wins — leaving higher amounts of free testosterone to convert to DHT. Although incidents of hair loss may not be as rife compared to anabolic steroids, androgenic alopecia is still possible on ostarine (and other SARMs). 

Ostarine Results (Before and After Pictures)

This user’s results are after taking 20mg/day of ostarine for 45 days, in combination with regular weight training.

This user lost 3kg (7lbs) in weight, yet looks considerably more muscular, due to greater levels of muscle definition. Thus, the scales may not be an accurate indicator of results when taking ostarine; due to simultaneous muscle-building and fat loss. Before and after pictures therefore are a must when monitoring progress before/after cycles.

Note: These results may exceed the average person’s experience, as this user mentioned he had been training more regularly on ostarine, thus contributing to some of the muscle gain and fat loss.